The article presents a histology-guided mathematical model to analyze tumor oxygenation, focusing on the sensitivity of various physical and computational parameters. The study involves a detailed examination of how different factors influence tumor oxygen levels, providing insights that could be crucial for cancer research and treatment strategies.

The government of Sierra Leone has reported the arrest of 13 military officials and one civilian following attacks in the nation's capital. These events occurred on a Sunday and resulted in 20 fatalities. Additionally, the attacks led to the escape of over 2,000 prisoners. The identities of those arrested have not been disclosed by the authorities. The situation is being described as an 'attempted coup', indicating a significant breach of national security and stability in the country.

Sierra Leone has arrested 13 military officials and one civilian following a failed coup attempt that resulted in 20 deaths and the release of over 2,000 prisoners. The incident has heightened tensions in Freetown, where security measures have been increased. President Julius Maada Bio, re-elected in June, faces a politically charged atmosphere with his main opponent rejecting the election results. The situation in Sierra Leone adds to regional instability, with recent successful coups in neighboring Guinea and Niger despite ECOWAS's non-coup policy.

Sierra Leone has arrested 13 military officials and one civilian following a failed coup attempt that resulted in 20 deaths and the release of over 2,000 prisoners. The incident has heightened tensions in Freetown, where security has been increased. President Julius Maada Bio, re-elected in June, faces a politically charged atmosphere with disputed election results. The situation in Sierra Leone adds to regional instability, with recent successful coups in neighboring Guinea and Niger despite ECOWAS's non-coup policy.

Authorities in Sierra Leone have arrested most of the leaders involved in an attempted break-in at key military sites, including the Wilberforce military barracks and the armory in Freetown. President Julius Maada Bio announced the arrests following a nationwide curfew imposed in response to the attacks. Security operations and investigations are ongoing, with calm reportedly restored in the capital.

Kel Mitchell provided a health update after being hospitalized with a bulging disc, reassuring fans of his recovery and expressing gratitude for their support. He detailed his symptoms and the medical care he received, emphasizing that the situation was less severe than initially feared. Mitchell is now recovering at home and continues to promote his upcoming projects, including the release of 'Good Burger 2' on Paramount+ and his appearance on the VH1 game show 'Celebrity Squares'.

The study characterizes the notch sensitivity of additively manufactured Inconel 718 produced by laser powder bed fusion. It evaluates the tensile strength of V-notched and smooth specimens in different orientations, using both total axial strain and localized notch diametral strain measurements, complemented by finite element analysis. Results indicate that notched specimens have higher tensile strength than smooth specimens, suggesting notch strengthening due to increased triaxial stress. Fractography analysis reveals a dominant ductile failure mode, with ductility decreasing with smaller notch root radii. The study concludes that L-PBF Inconel 718 material exhibits notch strengthening and isotropic tensile material performance, with further research needed on complex loading behaviors.

President Julius Maada Bio was re-elected in Sierra Leone, narrowly avoiding a runoff by securing 56 percent of the vote. His main opponent, Samura Kamara, who received 41 percent, rejected the results as not credible. Bio was sworn in an hour after the results were announced, amidst celebrations by his supporters. The election was a repeat of the 2018 contest, and comes at a time when Sierra Leone faces severe economic challenges, including high inflation, unemployment, and food insecurity.

Senior officials from Sierra Leone’s main opposition party accused the military of using live ammunition and tear gas at their headquarters in Freetown, raising tensions after presidential elections. The opposition candidate, Samura Kamara, and his supporters were reviewing election data when the military intervened. The police claimed they acted to disperse a crowd that was harassing people, but reports of live ammunition could not be confirmed. The incident highlights the volatile political climate in Sierra Leone following the elections.

Julius Maada Bio, president of Sierra Leone since 2018, has allocated 22 percent of the national budget to education, resulting in one million additional children attending school. As Sierra Leoneans voted for their next president, Bio highlighted this education initiative, although voters are also concerned with inflation, unemployment, power cuts, and climate change-related heat waves. Polling stations experienced delays due to missing electoral materials or officials.

Eugenia Kargbo, Freetown's first chief heat officer, aims to revitalize the city by addressing the challenges posed by rising temperatures and climate change. Despite the city's growth and the prevalence of informal housing, Kargbo is tasked with making Freetown verdant and livable once again, amidst the backdrop of the city's struggles with landslides, floods, and heat waves.

Skyrocketing fuel prices, partly due to the war in Ukraine, have significantly increased the cost of living in Sierra Leone, severely impacting fishermen and working-class communities. Fishermen like Edison Fofana face rising costs for essential supplies such as ice, fuel, and nets, while foreign trawlers deplete local fish stocks, forcing them to venture further out to sea. The economic strain has led to food insecurity, with 48 million people in West and Central Africa expected to face hunger next year. Local efforts, such as a government-financed ice storage container, have been hampered by infrastructure issues, exacerbating the challenges faced by the fishing community.

The study investigates the seasonal roost selection and activity of northern myotis bats in Pennsylvania, focusing on differences between male and female roosts and the impact of white-nose syndrome (WNS). The research highlights that female bats prefer roosts close to water and in dense forests, while both sexes favor declining or dead trees. The study also identifies non-traditional hibernacula, such as underground voids, used by these bats, suggesting that some populations are sedentary and do not migrate. The findings emphasize the need for targeted conservation efforts to protect these critical habitats year-round.

The study explores the development of a SARS-CoV-2 antigen test using Simoa technology to detect N-protein in various sample matrices, including serum, plasma, dried blood microsamples (DBS), and saliva. The test shows high positive percent agreement (PPA) and negative percent agreement (NPA) with PCR tests, indicating its potential as a robust diagnostic tool for both asymptomatic and symptomatic COVID-19 patients. The research highlights the correlation between N-protein levels and disease severity, as well as the inverse relationship between N-protein and anti-SARS-CoV-2 spike protein IgG. The study suggests that early IgG response may alleviate severe disease outcomes and emphasizes the need for further clinical validation.

Kamala Harris' rise to Vice President-elect is celebrated as a continuation of the legacy of civil rights pioneers like Ruby Nell Bridges Hall. The article highlights the historical significance of Harris and President-elect Joseph Biden's upcoming tenure, drawing parallels to past civil rights milestones. It underscores the importance of remembering the contributions of those who paved the way, such as Ruby Nell and her teacher Barbara Henry, and emphasizes the need for a focused and honorable purpose in leadership.

Joseph Johnson, a retired Veterans Affairs employee, agrees with James Gill's view that wealthy Catholics should not naively earmark donations to the church, suggesting instead that they should establish an independent foundation to provide counseling to victims of sexual abuse by the church. He criticizes the Catholic Church for not being transparent about the number of abuse victims and suggests that the Louisiana Attorney General, Jeff Landry, is covering up by not investigating the church's actions.